William R Shanahan Selected Research

lorcaserin

1/2020	Lorcaserin: A review of its preclinical and clinical pharmacology and therapeutic potential.
8/2017	Lorcaserin for Smoking Cessation and Associated Weight Gain: A Randomized 12-Week Clinical Trial.
10/2014	Early weight loss while on lorcaserin, diet and exercise as a predictor of week 52 weight-loss outcomes.
7/2013	Echocardiographic assessment of cardiac valvular regurgitation with lorcaserin from analysis of 3 phase 3 clinical trials.
7/2012	Randomized placebo-controlled clinical trial of lorcaserin for weight loss in type 2 diabetes mellitus: the BLOOM-DM study.
10/2011	A one-year randomized trial of lorcaserin for weight loss in obese and overweight adults: the BLOSSOM trial.
7/2010	Multicenter, placebo-controlled trial of lorcaserin for weight management.
3/2009	Lorcaserin (APD356), a selective 5-HT(2C) agonist, reduces body weight in obese men and women.

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William R Shanahan Research Topics

Disease

6	Weight Loss (Weight Reduction) 10/2014 - 03/2009
5	Body Weight (Weight, Body) 01/2020 - 03/2009
3	Overweight 07/2012 - 07/2010
2	Obesity 01/2020 - 07/2012
2	Weight Gain 01/2020 - 08/2017
2	Type 2 Diabetes Mellitus (MODY) 10/2014 - 07/2012
2	Headache (Headaches) 10/2011 - 07/2010
2	Dizziness (Lightheadedness) 10/2011 - 07/2010
2	Nausea 10/2011 - 07/2010
2	Anaphylaxis (Anaphylactic Shock) 01/2004 - 03/2003
1	Pain (Aches) 01/2020
1	Bulimia (Binge Eating) 01/2020
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2018
1	Proteinuria 01/2018
1	Hypoglycemia (Reactive Hypoglycemia) 07/2012
1	Diabetes Mellitus 07/2012
1	Food Hypersensitivity (Food Allergy) 12/2003
1	Peanut Hypersensitivity (Peanut Allergy) 03/2003
1	Crohn Disease (Crohn's Disease) 03/2002
1	Rheumatoid Arthritis 03/2002

Drug/Important Bio-Agent (IBA)

8	lorcaserinIBA 01/2020 - 03/2009
3	anti-IgE antibodiesIBA 01/2004 - 03/2003
1	B-Cell Activating FactorIBA 01/2018
1	AMG623 peptibodyIBA 01/2018
1	Antinuclear AntibodiesIBA 01/2018
1	Estrogens (Estrogen)FDA Link 01/2018
1	SteroidsIBA 01/2018
1	Biomarkers (Surrogate Marker)IBA 01/2018
1	W 12IBA 10/2014
1	5-HT2C Serotonin ReceptorIBA 07/2010
1	Dihydrotachysterol (AT 10)IBA 03/2009
1	VaccinesIBA 01/2004
1	Proteins (Proteins, Gene)FDA Link 01/2004
1	Immunoglobulin E (IgE)IBA 03/2003
1	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 03/2002
1	alicaforsenIBA 03/2002
1	OligodeoxyribonucleotidesIBA 03/2002
1	Pharmaceutical PreparationsIBA 03/2002

Therapy/Procedure

3	Therapeutics 01/2004 - 03/2003
1	Glycemic Control 07/2012